INDRA statements for KCNH8

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Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid lincs_drug tas hprd trrust ctd virhostnet phosphoelm drugbank omnipath | geneways tees isi trips rlimsp medscan sparser eidos reach
reading
KCNH8 affects FABP5
| 2
KCNH8 binds FABP5. 1 / 1
| 1
sparser
"ERG and SPINK1 are already associated with outcome; however, FABP5 and KCNH8 have not been associated with outcome."
22811706
SPINK1 binds KCNH8, ERG, FABP5, and PAH. 1 / 1
| 1
sparser
"Several genes like ERG, FABP5, SPINK1, KCNH8, and PAH are highly associated with outcome data."
22811706
KCNH8 affects ERG
| 1 1
KCNH8 binds ERG. 1 / 1
| 1
reach
"This might explain the association between KCNH8 and ERG."
22811706
SPINK1 binds KCNH8, ERG, FABP5, and PAH. 1 / 1
| 1
sparser
"Several genes like ERG, FABP5, SPINK1, KCNH8, and PAH are highly associated with outcome data."
22811706
FABP5 affects KCNH8
| 2
KCNH8 binds FABP5. 1 / 1
| 1
sparser
"ERG and SPINK1 are already associated with outcome; however, FABP5 and KCNH8 have not been associated with outcome."
22811706
SPINK1 binds KCNH8, ERG, FABP5, and PAH. 1 / 1
| 1
sparser
"Several genes like ERG, FABP5, SPINK1, KCNH8, and PAH are highly associated with outcome data."
22811706
ERG affects KCNH8
| 1 1
KCNH8 binds ERG. 1 / 1
| 1
reach
"This might explain the association between KCNH8 and ERG."
22811706
SPINK1 binds KCNH8, ERG, FABP5, and PAH. 1 / 1
| 1
sparser
"Several genes like ERG, FABP5, SPINK1, KCNH8, and PAH are highly associated with outcome data."
22811706
Phosphatidylinositol phosphate affects KCNH8
| 1
Phosphatidylinositol phosphate inhibits KCNH8. 1 / 1
| 1
reach
"A recent study has shown that PIP 2 inhibits hELK1 by interacting with some of the positively charged residues in the S4-S5 linker, S6, and EAG domain XREF_BIBR."
27005320
Phosphatidylinositol affects KCNH8
| 1
Phosphatidylinositol inhibits KCNH8. 1 / 1
| 1
reach
"Previously, it has been shown that hELK1 is downregulated by PI (4,5) P 2."
28443815
Imatinib affects KCNH8
| 1
Imatinib inhibits KCNH8. 1 / 1
| 1
reach
"The results confirm a set of EPoC predictions, including induction of CPNE8 by NDN, induction of KCNH8 by PDGF-AA protein dimers (i.e., a PDGFRA agonist) and suppression of KCNH8 by Imatinib (a selective inhibitor of PDGFRA and other tyrosine kinases)."
21525872
Hsa-miR-335-5p affects KCNH8
1 |
Transcriptionally active hsa-miR-335-5p decreases the amount of KCNH8. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
18185580
PDGF-AA protein dimers affects KCNH8
| 1
PDGF-AA protein dimers activates KCNH8. 1 / 1
| 1
reach
"The results confirm a set of EPoC predictions, including induction of CPNE8 by NDN, induction of KCNH8 by PDGF-AA protein dimers (i.e., a PDGFRA agonist) and suppression of KCNH8 by Imatinib (a selective inhibitor of PDGFRA and other tyrosine kinases)."
21525872
ERG affects FABP5, KCNH8, PAH, and SPINK1
| 1
SPINK1 binds KCNH8, ERG, FABP5, and PAH. 1 / 1
| 1
sparser
"Several genes like ERG, FABP5, SPINK1, KCNH8, and PAH are highly associated with outcome data."
22811706
BABAM2 affects KCNH8
| 1
BABAM2 activates KCNH8. 1 / 1
| 1
reach
"BRE, which encodes a death receptor associated anti-apoptotic protein with an inhibitory function in the mitochondrial pathway, was the most up-regulated, followed by FLJ242562, R55784, MMP12, and KCNH8."
20021671
APP affects KCNH8
1 |
Transcriptionally active APP decreases the amount of KCNH8. 1 / 1
1 |
biopax:ctd
No evidence text available
21298039