"Kv6.3 does not form a functional voltage-gated ion channel when expressed by itself, but when Kv6.3 and Kv2.1 were co-expressed, the heteromultimeric channels display a decreased rate of deactivation compared to that of the homomultimeric Kv2.1 channels."
"Kv6.3 does not form a functional voltage-gated ion channel when expressed by itself, but when Kv6.3 and Kv2.1 were co-expressed, the heteromultimeric channels display a decreased rate of deactivation compared to that of the homomultimeric Kv2.1 channels."
"Among these targets, high expression levels of six genes (THBS2, P4HA3, SERPINH1, CDH11, BCAT1, and KCNG3) were closely associated with a poor prognosis (10-year survival rates) in GC patients (p < 0.05) according to TCGA database analyses."
"Among these targets, high expression levels of six genes (THBS2, P4HA3, SERPINH1, CDH11, BCAT1, and KCNG3) were closely associated with a poor prognosis (10-year survival rates) in GC patients (p < 0.05) according to TCGA database analyses."
"Using a yeast two-hybrid assay, we found that substitution of the corresponding histidine 105 in Kv2.1 by valine (H105V) or arginine (H105R) disrupted the interaction of the T1 domain of Kv2.1 with the T1 domains of both Kv6.3 and Kv6.4, whereas interaction of the T1 domain of Kv2.1 with itself was unaffected by this mutation."